Keystone College had a total enrollment of 952 students in 2024. The full-time enrollment at Keystone College is 665 students and the part-time enrollment is 287. This means that 69.9% of students enrolled at Keystone College are enrolled full-time.

The enrolled student population at Keystone College, both undergraduate and graduate, is 63% White, 15.1% Black or African American, 8.72% Hispanic or Latino, 3.57% Two or More Races, 0.525% American Indian or Alaska Native, 0.42% Asian, and 0.105% Native Hawaiian or Other Pacific Islanders.

Students enrolled at Keystone College in full-time Undergraduate programs are most commonly White Male (34.5%), followed by White Female (34.4%) and Black or African American Male (15.2%). Students enrolled in full-time Graduate programs are most commonly White Female (40.7%), followed by White Male (32.2%) and Black or African American Male (10.2%).