Charleston Southern University had a total enrollment of 3,832 students in 2024. The full-time enrollment at Charleston Southern University is 3,110 students and the part-time enrollment is 722. This means that 81.2% of students enrolled at Charleston Southern University are enrolled full-time.

The enrolled student population at Charleston Southern University, both undergraduate and graduate, is 60.3% White, 17.9% Black or African American, 7.78% Hispanic or Latino, 4.46% Two or More Races, 1.44% Asian, 0.209% American Indian or Alaska Native, and 0.209% Native Hawaiian or Other Pacific Islanders.

Students enrolled at Charleston Southern University in full-time Undergraduate programs are most commonly White Female (38.1%), followed by White Male (20.8%) and Black or African American Female (9.4%). Students enrolled in full-time Graduate programs are most commonly White Female (47.3%), followed by White Male (19.9%) and Black or African American Female (9.29%).