Ohio State University-Main Campus had a total enrollment of 61,443 students in 2024. The full-time enrollment at Ohio State University-Main Campus is 53,237 students and the part-time enrollment is 8,206. This means that 86.6% of students enrolled at Ohio State University-Main Campus are enrolled full-time.

The enrolled student population at Ohio State University-Main Campus, both undergraduate and graduate, is 58.4% White, 10.1% Asian, 7.67% Black or African American, 5.8% Hispanic or Latino, 4.51% Two or More Races, 0.0602% American Indian or Alaska Native, and 0.0439% Native Hawaiian or Other Pacific Islanders.

Students enrolled at Ohio State University-Main Campus in full-time Undergraduate programs are most commonly White Female (31%), followed by White Male (29.7%) and Asian Male (5.31%). Students enrolled in full-time Graduate programs are most commonly White Female (33.9%), followed by White Male (19.2%) and Asian Female (5.06%).