William Penn University had a total enrollment of 1,425 students in 2024. The full-time enrollment at William Penn University is 1,277 students and the part-time enrollment is 148. This means that 89.6% of students enrolled at William Penn University are enrolled full-time.

The enrolled student population at William Penn University, both undergraduate and graduate, is 57.1% White, 16.9% Black or African American, 9.26% Hispanic or Latino, 5.96% Two or More Races, 0.842% American Indian or Alaska Native, 0.561% Native Hawaiian or Other Pacific Islanders, and 0.211% Asian.

Students enrolled at William Penn University in full-time Undergraduate programs are most commonly White Female (32.9%), followed by White Male (22.5%) and Black or African American Male (14.3%). Students enrolled in full-time Graduate programs are most commonly White Male (21.7%), followed by White Female (16.3%) and Hispanic or Latino Female (8.7%).