University of Illinois Springfield had a total enrollment of 4,628 students in 2024. The full-time enrollment at University of Illinois Springfield is 2,725 students and the part-time enrollment is 1,903. This means that 58.9% of students enrolled at University of Illinois Springfield are enrolled full-time.

The enrolled student population at University of Illinois Springfield, both undergraduate and graduate, is 48.2% White, 13% Black or African American, 8.71% Hispanic or Latino, 4.47% Asian, 3.52% Two or More Races, 0.108% American Indian or Alaska Native, and 0.108% Native Hawaiian or Other Pacific Islanders.

Students enrolled at University of Illinois Springfield in full-time Undergraduate programs are most commonly White Female (34%), followed by White Male (25.7%) and Black or African American Female (8.5%). Students enrolled in full-time Graduate programs are most commonly White Female (11.3%), followed by White Male (8.13%) and Black or African American Female (5.28%).