Trine University had a total enrollment of 4,646 students in 2024. The full-time enrollment at Trine University is 2,562 students and the part-time enrollment is 2,084. This means that 55.1% of students enrolled at Trine University are enrolled full-time.

The enrolled student population at Trine University, both undergraduate and graduate, is 79.4% White, 7.1% Hispanic or Latino, 4.52% Black or African American, 3.01% Two or More Races, 2.32% Asian, 0.301% American Indian or Alaska Native, and 0.0646% Native Hawaiian or Other Pacific Islanders.

Students enrolled at Trine University in full-time Undergraduate programs are most commonly White Male (50.7%), followed by White Female (32.6%) and Black or African American Male (3.86%). Students enrolled in full-time Graduate programs are most commonly White Female (56.6%), followed by White Male (20.2%) and Hispanic or Latino Female (4.09%).