National Polytechnic College had a total enrollment of 516 students in 2024. The full-time enrollment at National Polytechnic College is 494 students and the part-time enrollment is 22. This means that 95.7% of students enrolled at National Polytechnic College are enrolled full-time.

The enrolled student population at National Polytechnic College, both undergraduate and graduate, is 58.9% Hispanic or Latino, 13.4% Asian, 13% White, 8.33% Black or African American, 2.52% Two or More Races, 2.33% American Indian or Alaska Native, and 0.581% Native Hawaiian or Other Pacific Islanders.

Students enrolled at National Polytechnic College in full-time Undergraduate programs are most commonly Hispanic or Latino Female (44.3%), followed by Hispanic or Latino Male (16.3%) and White Female (9.11%).