Missouri Valley College had a total enrollment of 1,770 students in 2024. The full-time enrollment at Missouri Valley College is 1,438 students and the part-time enrollment is 332. This means that 81.2% of students enrolled at Missouri Valley College are enrolled full-time.

The enrolled student population at Missouri Valley College, both undergraduate and graduate, is 41.8% White, 12.8% Hispanic or Latino, 12.2% Black or African American, 3.73% Two or More Races, 0.734% Native Hawaiian or Other Pacific Islanders, 0.508% American Indian or Alaska Native, and 0.395% Asian.

Students enrolled at Missouri Valley College in full-time Undergraduate programs are most commonly White Female (19.4%), followed by White Male (16.7%) and Black or African American Male (11.8%). Students enrolled in full-time Graduate programs are most commonly White Female (28.3%), followed by Black or African American Female (6.67%) and Two or More Races Female (6.67%).