American National University-Pikeville had a total enrollment of 444 students in 2024. The full-time enrollment at American National University-Pikeville is 252 students and the part-time enrollment is 192. This means that 56.8% of students enrolled at American National University-Pikeville are enrolled full-time.

The enrolled student population at American National University-Pikeville, both undergraduate and graduate, is 47.5% White, 25.7% Black or African American, 11.9% Asian, 8.56% Hispanic or Latino, 4.28% Two or More Races, 0.901% American Indian or Alaska Native, and 0.45% Native Hawaiian or Other Pacific Islanders.

Students enrolled at American National University-Pikeville in full-time Undergraduate programs are most commonly White Female (60.4%), followed by Black or African American Female (15.5%) and Hispanic or Latino Female (6.96%). Students enrolled in full-time Graduate programs are most commonly Asian Male (31.5%), followed by Asian Female (24.2%) and Black or African American Female (14.8%).