Southeast Missouri Hospital College of Nursing and Health Sciences had a total enrollment of 202 students in 2024. The full-time enrollment at Southeast Missouri Hospital College of Nursing and Health Sciences is 110 students and the part-time enrollment is 92. This means that 54.5% of students enrolled at Southeast Missouri Hospital College of Nursing and Health Sciences are enrolled full-time.

The enrolled student population at Southeast Missouri Hospital College of Nursing and Health Sciences, both undergraduate and graduate, is 84.7% White, 7.92% Black or African American, 3.47% Hispanic or Latino, 1.49% Asian, 1.49% Two or More Races, and 0.495% American Indian or Alaska Native.

Students enrolled at Southeast Missouri Hospital College of Nursing and Health Sciences in full-time Undergraduate programs are most commonly White Female (70.8%), followed by White Male (12.4%) and Black or African American Female (6.49%).