Central Oklahoma College had a total enrollment of 477 students in 2024. The full-time enrollment at Central Oklahoma College is 261 students and the part-time enrollment is 216. This means that 54.7% of students enrolled at Central Oklahoma College are enrolled full-time.

The enrolled student population at Central Oklahoma College, both undergraduate and graduate, is 34.6% White, 28.1% Black or African American, 17.6% Hispanic or Latino, 13.4% Two or More Races, 3.35% American Indian or Alaska Native, 1.26% Asian, and 0.419% Native Hawaiian or Other Pacific Islanders.

Students enrolled at Central Oklahoma College in full-time Undergraduate programs are most commonly Black or African American Female (31.8%), followed by White Female (27.4%) and Hispanic or Latino Female (13.2%).