Colorado Mesa University had a total enrollment of 9,785 students in 2024. The full-time enrollment at Colorado Mesa University is 7,280 students and the part-time enrollment is 2,505. This means that 74.4% of students enrolled at Colorado Mesa University are enrolled full-time.

The enrolled student population at Colorado Mesa University, both undergraduate and graduate, is 64.2% White, 20.6% Hispanic or Latino, 3.89% Two or More Races, 1.47% Asian, 1.38% Black or African American, 0.634% American Indian or Alaska Native, and 0.327% Native Hawaiian or Other Pacific Islanders.

Students enrolled at Colorado Mesa University in full-time Undergraduate programs are most commonly White Female (34.5%), followed by White Male (29.2%) and Hispanic or Latino Female (11.7%). Students enrolled in full-time Graduate programs are most commonly White Female (50%), followed by White Male (25.6%) and Hispanic or Latino Female (10.9%).